BDBM50345187 4-(4-oxo-3,4-dihydro-2H-benzo[h]chromen-2-yl)benzonitrile::CHEMBL255108

SMILES: O=C1CC(Oc2c1ccc1ccccc21)c1ccc(cc1)C#N

InChI Key: InChIKey=LIUTUDSSIWWZTA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50345187 (4-(4-oxo-3,4-dihydro-2H-benzo[h]chromen-2-yl)benzo...) Show SMILES O=C1CC(Oc2c1ccc1ccccc21)c1ccc(cc1)C#N Show InChI InChI=1S/C20H13NO2/c21-12-13-5-7-15(8-6-13)19-11-18(22)17-10-9-14-3-1-2-4-16(14)20(17)23-19/h1-10,19H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales Curated by ChEMBL					Assay Description Inhibition of human aromatase in placental microsomes				Bioorg Med Chem 16: 1474-80 (2008) Article DOI: 10.1016/j.bmc.2007.10.057 BindingDB Entry DOI: 10.7270/Q2DR2WCC
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50345187 (4-(4-oxo-3,4-dihydro-2H-benzo[h]chromen-2-yl)benzo...) Show SMILES O=C1CC(Oc2c1ccc1ccccc21)c1ccc(cc1)C#N Show InChI InChI=1S/C20H13NO2/c21-12-13-5-7-15(8-6-13)19-11-18(22)17-10-9-14-3-1-2-4-16(14)20(17)23-19/h1-10,19H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 4021 Biomol�cules et Th�rapies anti-tumorales Curated by ChEMBL					Assay Description Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...				Eur J Med Chem 46: 2541-5 (2011) Article DOI: 10.1016/j.ejmech.2011.03.043 BindingDB Entry DOI: 10.7270/Q2MC90CB
					More data for this Ligand-Target Pair