null

SMILES: OC(=O)c1cc2cc(ccc2o1)-c1cncc(NC2CCNCC2)n1

InChI Key: InChIKey=PWLTUXUDBOARFK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345244   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50345244 (5-(6-(piperidin-4-ylamino)pyrazin-2-yl)benzofuran-...) Show SMILES OC(=O)c1cc2cc(ccc2o1)-c1cncc(NC2CCNCC2)n1 Show InChI InChI=1S/C18H18N4O3/c23-18(24)16-8-12-7-11(1-2-15(12)25-16)14-9-20-10-17(22-14)21-13-3-5-19-6-4-13/h1-2,7-10,13,19H,3-6H2,(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Inhibition of human Pim2 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 90 mins by off-chip mobility shift method				Bioorg Med Chem Lett 21: 3050-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.030 BindingDB Entry DOI: 10.7270/Q2ZP46GG
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50345244 (5-(6-(piperidin-4-ylamino)pyrazin-2-yl)benzofuran-...) Show SMILES OC(=O)c1cc2cc(ccc2o1)-c1cncc(NC2CCNCC2)n1 Show InChI InChI=1S/C18H18N4O3/c23-18(24)16-8-12-7-11(1-2-15(12)25-16)14-9-20-10-17(22-14)21-13-3-5-19-6-4-13/h1-2,7-10,13,19H,3-6H2,(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift method				Bioorg Med Chem Lett 21: 3050-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.030 BindingDB Entry DOI: 10.7270/Q2ZP46GG
					More data for this Ligand-Target Pair