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SMILES: Cc1cc(NC2CC2)n2ncnc2n1

InChI Key: InChIKey=VTIPUIBERMOAOI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345398   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Plasmodium falciparum)		BDBM50345398
PNG
(CHEMBL1784582 | N-Cyclopropyl-5-methyl-[1,2,4]tria...)
Show SMILES Cc1cc(NC2CC2)n2ncnc2n1
Show InChI InChI=1S/C9H11N5/c1-6-4-8(13-7-2-3-7)14-9(12-6)10-5-11-14/h4-5,7,13H,2-3H2,1H3
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Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...

J Med Chem 54: 3935-49 (2011)


Article DOI: 10.1021/jm200265b
BindingDB Entry DOI: 10.7270/Q2FN16HS
More data for this
Ligand-Target Pair