BindingDB logo
myBDB logout

null

SMILES: Cc1cc(Nc2ccc(cc2)N2CCOCC2)n2ncnc2n1

InChI Key: InChIKey=HCJBGFOJFCXBIG-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345410   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Plasmodium falciparum)		BDBM50345410
PNG
(CHEMBL1784570 | N-(4-Morpholinophenyl)-5-methyl-[1...)
Show SMILES Cc1cc(Nc2ccc(cc2)N2CCOCC2)n2ncnc2n1
Show InChI InChI=1S/C16H18N6O/c1-12-10-15(22-16(19-12)17-11-18-22)20-13-2-4-14(5-3-13)21-6-8-23-9-7-21/h2-5,10-11,20H,6-9H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...

J Med Chem 54: 3935-49 (2011)


Article DOI: 10.1021/jm200265b
BindingDB Entry DOI: 10.7270/Q2FN16HS
More data for this
Ligand-Target Pair