BDBM50345427 CHEMBL1784585::N-Cyclohexyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

SMILES: Cc1cc(NC2CCCCC2)n2ncnc2n1

InChI Key: InChIKey=LABDAERVBUYDMB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM50345427 (CHEMBL1784585 | N-Cyclohexyl-5-methyl-[1,2,4]triaz...) Show SMILES Cc1cc(NC2CCCCC2)n2ncnc2n1 Show InChI InChI=1S/C12H17N5/c1-9-7-11(16-10-5-3-2-4-6-10)17-12(15-9)13-8-14-17/h7-8,10,16H,2-6H2,1H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington Curated by ChEMBL					Assay Description Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...				J Med Chem 54: 3935-49 (2011) Article DOI: 10.1021/jm200265b BindingDB Entry DOI: 10.7270/Q2FN16HS
					More data for this Ligand-Target Pair