BDBM50345439 5-methyl-6-propyl-N-p-tolyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::CHEMBL1784716

SMILES: CCCc1c(C)nc2ncnn2c1Nc1ccc(C)cc1

InChI Key: InChIKey=RDLSGYWFNSVDNC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50345439 (5-methyl-6-propyl-N-p-tolyl-[1,2,4]triazolo[1,5-a]...) Show SMILES CCCc1c(C)nc2ncnn2c1Nc1ccc(C)cc1 Show InChI InChI=1S/C16H19N5/c1-4-5-14-12(3)19-16-17-10-18-21(16)15(14)20-13-8-6-11(2)7-9-13/h6-10,20H,4-5H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington Curated by ChEMBL					Assay Description Inhibition of His6-tagged recombinant human dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 t...				J Med Chem 54: 3935-49 (2011) Article DOI: 10.1021/jm200265b BindingDB Entry DOI: 10.7270/Q2FN16HS
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM50345439 (5-methyl-6-propyl-N-p-tolyl-[1,2,4]triazolo[1,5-a]...) Show SMILES CCCc1c(C)nc2ncnn2c1Nc1ccc(C)cc1 Show InChI InChI=1S/C16H19N5/c1-4-5-14-12(3)19-16-17-10-18-21(16)15(14)20-13-8-6-11(2)7-9-13/h6-10,20H,4-5H2,1-3H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington Curated by ChEMBL					Assay Description Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...				J Med Chem 54: 3935-49 (2011) Article DOI: 10.1021/jm200265b BindingDB Entry DOI: 10.7270/Q2FN16HS
					More data for this Ligand-Target Pair