BDBM50345690 (3-endo)-3-[2-Hydroxy-2,2-bis(4-methyl-3-thienyl)ethyl]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide::CHEMBL1785080

SMILES: Cc1cc(cs1)C(O)(CC1C[C@H]2CC[C@H](C1)[N+]2(C)C)c1csc(C)c1

InChI Key: InChIKey=HUZZFQHMHDDOBG-WOJBJXKFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50345690 ((3-endo)-3-[2-Hydroxy-2,2-bis(4-methyl-3-thienyl)e...) Show SMILES Cc1cc(cs1)C(O)(CC1C[C@H]2CC[C@H](C1)[N+]2(C)C)c1csc(C)c1 |r,TLB:8:9:16:12.13| Show InChI InChI=1S/C21H30NOS2/c1-14-7-17(12-24-14)21(23,18-8-15(2)25-13-18)11-16-9-19-5-6-20(10-16)22(19,3)4/h7-8,12-13,16,19-20,23H,5-6,9-11H2,1-4H3/q+1/t19-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FLIPR				J Med Chem 52: 5241-52 (2010) Article DOI: 10.1021/jm900736e BindingDB Entry DOI: 10.7270/Q2PK0H54
					More data for this Ligand-Target Pair