BDBM50346014 (S)-2-(4-(isopropylsulfonyl)-2-oxopyridin-1(2H)-yl)-4-methyl-N-(5-methylpyridin-2-yl)pentanamide::CHEMBL1783727

SMILES: CC(C)C[C@@H](C(=O)Nc1ccc(C)cn1)n1ccc(cc1=O)S(=O)(=O)C(C)C

InChI Key: InChIKey=OLGWAOITYSCNSL-KRWDZBQOSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50346014 ((S)-2-(4-(isopropylsulfonyl)-2-oxopyridin-1(2H)-yl...) Show SMILES CC(C)C[C@@H](C(=O)Nc1ccc(C)cn1)n1ccc(cc1=O)S(=O)(=O)C(C)C |r| Show InChI InChI=1S/C20H27N3O4S/c1-13(2)10-17(20(25)22-18-7-6-15(5)12-21-18)23-9-8-16(11-19(23)24)28(26,27)14(3)4/h6-9,11-14,17H,10H2,1-5H3,(H,21,22,25)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometry				Bioorg Med Chem Lett 19: 3247-52 (2009) Article DOI: 10.1016/j.bmcl.2009.04.107 BindingDB Entry DOI: 10.7270/Q2PZ595B
					More data for this Ligand-Target Pair