null

SMILES: Cc1nc(nc(Nc2ccc(cc2)C(O)=O)c1CC=C)-c1ccsc1

InChI Key: InChIKey=WWYXEOMOYWZPDT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50346104 (4-(5-allyl-6-methyl-2-(thiophen-3-yl)pyrimidin-4-y...) Show SMILES Cc1nc(nc(Nc2ccc(cc2)C(O)=O)c1CC=C)-c1ccsc1 Show InChI InChI=1S/C19H17N3O2S/c1-3-4-16-12(2)20-17(14-9-10-25-11-14)22-18(16)21-15-7-5-13(6-8-15)19(23)24/h3,5-11H,1,4H2,2H3,(H,23,24)(H,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4D3 incubated for 10 mins using cAMP and [3H]cAMP substrates				Bioorg Med Chem Lett 19: 3174-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.121 BindingDB Entry DOI: 10.7270/Q26110NQ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50346104 (4-(5-allyl-6-methyl-2-(thiophen-3-yl)pyrimidin-4-y...) Show SMILES Cc1nc(nc(Nc2ccc(cc2)C(O)=O)c1CC=C)-c1ccsc1 Show InChI InChI=1S/C19H17N3O2S/c1-3-4-16-12(2)20-17(14-9-10-25-11-14)22-18(16)21-15-7-5-13(6-8-15)19(23)24/h3,5-11H,1,4H2,2H3,(H,23,24)(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substrates				Bioorg Med Chem Lett 19: 3174-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.121 BindingDB Entry DOI: 10.7270/Q26110NQ
					More data for this Ligand-Target Pair