BDBM50346178 8-methyl-3-(pyridin-3-yl)-8-azabicyclo[3.2.1]oct-2-ene dihydrochloride::CHEMBL1783887

SMILES: CN1C2CCC1C=C(C2)c1cccnc1

InChI Key: InChIKey=OZAJXVSFXYHSBL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50346178 (8-methyl-3-(pyridin-3-yl)-8-azabicyclo[3.2.1]oct-2...) Show SMILES CN1C2CCC1C=C(C2)c1cccnc1 |c:7| Show InChI InChI=1S/C13H16N2/c1-15-12-4-5-13(15)8-11(7-12)10-3-2-6-14-9-10/h2-3,6-7,9,12-13H,4-5,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Swiss Federal Institute of Technology Zurich Curated by ChEMBL					Assay Description Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenates				J Med Chem 48: 5123-30 (2005) Article DOI: 10.1021/jm040881a BindingDB Entry DOI: 10.7270/Q2PR7ZQ2
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-7 subunit (Mus musculus)	BDBM50346178 (8-methyl-3-(pyridin-3-yl)-8-azabicyclo[3.2.1]oct-2...) Show SMILES CN1C2CCC1C=C(C2)c1cccnc1 |c:7| Show InChI InChI=1S/C13H16N2/c1-15-12-4-5-13(15)8-11(7-12)10-3-2-6-14-9-10/h2-3,6-7,9,12-13H,4-5,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Targacept, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membrane				Bioorg Med Chem Lett 19: 4359-63 (2009) Article DOI: 10.1016/j.bmcl.2009.05.085 BindingDB Entry DOI: 10.7270/Q2DJ5FZP
					More data for this Ligand-Target Pair