BDBM50346375 4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-tricyclo [5.2.1.02,6]dec-8-ene-3,5-dione::CHEMBL1783351

SMILES: O=C1C2C3CC(C=C3)C2C(=O)N1OCCCN1CCN(CC1)c1cccc2ccccc12

InChI Key: InChIKey=RUFAUUMYKFPZQN-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50346375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50346375 (4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...) Show SMILES O=C1C2C3CC(C=C3)C2C(=O)N1OCCCN1CCN(CC1)c1cccc2ccccc12 |c:6| Show InChI InChI=1S/C26H29N3O3/c30-25-23-19-9-10-20(17-19)24(23)26(31)29(25)32-16-4-11-27-12-14-28(15-13-27)22-8-3-6-18-5-1-2-7-21(18)22/h1-3,5-10,19-20,23-24H,4,11-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.293	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation counting				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50346375 (4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...) Show SMILES O=C1C2C3CC(C=C3)C2C(=O)N1OCCCN1CCN(CC1)c1cccc2ccccc12 |c:6| Show InChI InChI=1S/C26H29N3O3/c30-25-23-19-9-10-20(17-19)24(23)26(31)29(25)32-16-4-11-27-12-14-28(15-13-27)22-8-3-6-18-5-1-2-7-21(18)22/h1-3,5-10,19-20,23-24H,4,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 mins				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50346375 (4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...) Show SMILES O=C1C2C3CC(C=C3)C2C(=O)N1OCCCN1CCN(CC1)c1cccc2ccccc12 |c:6| Show InChI InChI=1S/C26H29N3O3/c30-25-23-19-9-10-20(17-19)24(23)26(31)29(25)32-16-4-11-27-12-14-28(15-13-27)22-8-3-6-18-5-1-2-7-21(18)22/h1-3,5-10,19-20,23-24H,4,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	263	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation counting				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50346375 (4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-...) Show SMILES O=C1C2C3CC(C=C3)C2C(=O)N1OCCCN1CCN(CC1)c1cccc2ccccc12 |c:6| Show InChI InChI=1S/C26H29N3O3/c30-25-23-19-9-10-20(17-19)24(23)26(31)29(25)32-16-4-11-27-12-14-28(15-13-27)22-8-3-6-18-5-1-2-7-21(18)22/h1-3,5-10,19-20,23-24H,4,11-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation counting				Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J
					More data for this Ligand-Target Pair