BDBM50346446 4-[4-(3-benzo[b]thiophen-3-yl-3-hydroxypropylamino)piperidin-1-yl]benzonitrile::CHEMBL1782811

SMILES: OC(CCNC1CCN(CC1)c1ccc(cc1)C#N)c1csc2ccccc12

InChI Key: InChIKey=BLZFUNSVSSNHRB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50346446 (4-[4-(3-benzo[b]thiophen-3-yl-3-hydroxypropylamino...) Show SMILES OC(CCNC1CCN(CC1)c1ccc(cc1)C#N)c1csc2ccccc12 Show InChI InChI=1S/C23H25N3OS/c24-15-17-5-7-19(8-6-17)26-13-10-18(11-14-26)25-12-9-22(27)21-16-28-23-4-2-1-3-20(21)23/h1-8,16,18,22,25,27H,9-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from of SERT in rat midbrain homogenates after 5 mins by scintillation counting				J Med Chem 54: 3086-90 (2011) Article DOI: 10.1021/jm2000773 BindingDB Entry DOI: 10.7270/Q26T0N0M
					More data for this Ligand-Target Pair