BDBM50346458 (2S,5S,12S)-12-amino-N-benzyl-2-(4-hydroxybenzyl)-3,13-dioxo-1,4-diazacyclotridecane-5-carboxamide::CHEMBL1782884

SMILES: N[C@H]1CCCCCC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1

InChI Key: InChIKey=WESKKZCOSAUWJU-VABKMULXSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human))	BDBM50346458 ((2S,5S,12S)-12-amino-N-benzyl-2-(4-hydroxybenzyl)-...) Show SMILES N[C@H]1CCCCCC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C26H34N4O4/c27-21-10-6-1-2-7-11-22(25(33)28-17-19-8-4-3-5-9-19)29-26(34)23(30-24(21)32)16-18-12-14-20(31)15-13-18/h3-5,8-9,12-15,21-23,31H,1-2,6-7,10-11,16-17,27H2,(H,28,33)(H,29,34)(H,30,32)/t21-,22-,23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	193	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...				J Med Chem 54: 3779-92 (2011) Article DOI: 10.1021/jm200036n BindingDB Entry DOI: 10.7270/Q2348KPZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50346458 ((2S,5S,12S)-12-amino-N-benzyl-2-(4-hydroxybenzyl)-...) Show SMILES N[C@H]1CCCCCC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C26H34N4O4/c27-21-10-6-1-2-7-11-22(25(33)28-17-19-8-4-3-5-9-19)29-26(34)23(30-24(21)32)16-18-12-14-20(31)15-13-18/h3-5,8-9,12-15,21-23,31H,1-2,6-7,10-11,16-17,27H2,(H,28,33)(H,29,34)(H,30,32)/t21-,22-,23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of catalytic activity of recombinant human AP-N transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...				J Med Chem 54: 3779-92 (2011) Article DOI: 10.1021/jm200036n BindingDB Entry DOI: 10.7270/Q2348KPZ
					More data for this Ligand-Target Pair