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SMILES: CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cc(F)cc(F)c1

InChI Key: InChIKey=DXKWHLOIIWRXJR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346786   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))		BDBM50346786
PNG
(CHEMBL1795443)
Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cc(F)cc(F)c1
Show InChI InChI=1S/C19H16F2O3/c1-19(2,22)18-7-11-3-10-6-15(23-16(10)9-17(11)24-18)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,22H,7H2,1-2H3
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n/an/a 360n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay

Eur J Med Chem 46: 2386-96 (2011)


Article DOI: 10.1016/j.ejmech.2011.03.022
BindingDB Entry DOI: 10.7270/Q2WD40XF
More data for this
Ligand-Target Pair