BDBM50346863 CHEMBL1797640::US8765820, 5b
SMILES: NC1CC1c1ccc(NC(=O)c2ccccc2)cc1
InChI Key: InChIKey=FFYGOYSNGFPHEN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of LSD1 | Bioorg Med Chem 19: 3625-36 (2011) Article DOI: 10.1016/j.bmc.2011.01.046 BindingDB Entry DOI: 10.7270/Q23X870S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of LSD1 (unknown origin) | Eur J Med Chem 94: 163-74 (2015) Article DOI: 10.1016/j.ejmech.2015.02.060 BindingDB Entry DOI: 10.7270/Q2JQ12QF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano US Patent | Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... | US Patent US8765820 (2014) BindingDB Entry DOI: 10.7270/Q20P0XPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano US Patent | Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... | US Patent US8765820 (2014) BindingDB Entry DOI: 10.7270/Q20P0XPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano US Patent | Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... | US Patent US8765820 (2014) BindingDB Entry DOI: 10.7270/Q20P0XPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 2 (LSD2) (Mus musculus (Mouse)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano US Patent | Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... | US Patent US8765820 (2014) BindingDB Entry DOI: 10.7270/Q20P0XPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate... | Eur J Med Chem 94: 163-74 (2015) Article DOI: 10.1016/j.ejmech.2015.02.060 BindingDB Entry DOI: 10.7270/Q2JQ12QF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | Eur J Med Chem 94: 163-74 (2015) Article DOI: 10.1016/j.ejmech.2015.02.060 BindingDB Entry DOI: 10.7270/Q2JQ12QF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM50346863 (CHEMBL1797640 | US8765820, 5b) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | Eur J Med Chem 94: 163-74 (2015) Article DOI: 10.1016/j.ejmech.2015.02.060 BindingDB Entry DOI: 10.7270/Q2JQ12QF | |||||||||||
More data for this Ligand-Target Pair |