BDBM50347125 CHEMBL1797228

SMILES: CN(C)C(=O)c1cccc(c1)-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O

InChI Key: InChIKey=VOSUOERWSOSNOR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50347125 (CHEMBL1797228) Show SMILES CN(C)C(=O)c1cccc(c1)-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O Show InChI InChI=1S/C22H19BrF2N2O3/c1-13-9-19(30-12-15-7-8-16(24)11-18(15)25)20(23)22(29)27(13)17-6-4-5-14(10-17)21(28)26(2)3/h4-11H,12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as phosphorylation of fluorescently-labelled MK2 using Hsp27 peptide as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 21: 4059-65 (2011) Article DOI: 10.1016/j.bmcl.2011.04.120 BindingDB Entry DOI: 10.7270/Q25Q4WFH
					More data for this Ligand-Target Pair