BDBM50347200 CHEMBL1795752

SMILES: CN1CCN(CCOc2ccc3cc4oc(nc(=O)c4cc3c2)N2CCOCC2)CC1

InChI Key: InChIKey=LNKMISAJHWCYCR-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50347200 (CHEMBL1795752) Show SMILES CN1CCN(CCOc2ccc3cc4oc(nc(=O)c4cc3c2)N2CCOCC2)CC1 Show InChI InChI=1S/C23H28N4O4/c1-25-4-6-26(7-5-25)8-13-30-19-3-2-17-16-21-20(15-18(17)14-19)22(28)24-23(31-21)27-9-11-29-12-10-27/h2-3,14-16H,4-13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of purified DNA-PK by ADP-Glo Kinase assay				Bioorg Med Chem 19: 3983-94 (2011) Article DOI: 10.1016/j.bmc.2011.05.032 BindingDB Entry DOI: 10.7270/Q20Z73M7
					More data for this Ligand-Target Pair