BDBM50347412 CHEMBL1801555

SMILES: CCN(Cc1ccccc1Cl)c1ccc(cc1)C(=O)NCc1cccnc1

InChI Key: InChIKey=NGRNKVDQOCGKBM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50347412 (CHEMBL1801555) Show SMILES CCN(Cc1ccccc1Cl)c1ccc(cc1)C(=O)NCc1cccnc1 Show InChI InChI=1S/C22H22ClN3O/c1-2-26(16-19-7-3-4-8-21(19)23)20-11-9-18(10-12-20)22(27)25-15-17-6-5-13-24-14-17/h3-14H,2,15-16H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Myrexis, Inc. Curated by ChEMBL					Assay Description Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotide				J Med Chem 53: 8734-46 (2010) Article DOI: 10.1021/jm101145b BindingDB Entry DOI: 10.7270/Q26H4HSP
					More data for this Ligand-Target Pair