BDBM50347435 CHEMBL1801866

SMILES: Cc1c(Sc2ccc(cc2)C(=O)NCc2cccnc2)[nH]c2nc(N)nc(N)c12

InChI Key: InChIKey=SDAPSOQAKNSTLB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50347435 (CHEMBL1801866) Show SMILES Cc1c(Sc2ccc(cc2)C(=O)NCc2cccnc2)[nH]c2nc(N)nc(N)c12 Show InChI InChI=1S/C20H19N7OS/c1-11-15-16(21)25-20(22)27-17(15)26-19(11)29-14-6-4-13(5-7-14)18(28)24-10-12-3-2-8-23-9-12/h2-9H,10H2,1H3,(H,24,28)(H5,21,22,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Myrexis, Inc. Curated by ChEMBL					Assay Description Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotide				J Med Chem 53: 8734-46 (2010) Article DOI: 10.1021/jm101145b BindingDB Entry DOI: 10.7270/Q26H4HSP
					More data for this Ligand-Target Pair