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SMILES: Cn1cc(C2=C(C(=O)CBr)C(=O)NC2=O)c2ccccc12

InChI Key: InChIKey=LDEKCICSIPDOQM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347535   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM50347535
PNG
(CHEMBL1801637)
Show SMILES Cn1cc(C2=C(C(=O)CBr)C(=O)NC2=O)c2ccccc12 |c:4|
Show InChI InChI=1S/C15H11BrN2O3/c1-18-7-9(8-4-2-3-5-10(8)18)12-13(11(19)6-16)15(21)17-14(12)20/h2-5,7H,6H2,1H3,(H,17,20,21)
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n/an/a 5n/an/an/an/an/an/a



Instituto de Qui£?mica Medica-CSIC

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide substrate after 30 mins by Glow-type luminescence assay in presence of 1...

J Med Chem 54: 4042-56 (2011)


Article DOI: 10.1021/jm1016279
BindingDB Entry DOI: 10.7270/Q29887C1
More data for this
Ligand-Target Pair