BDBM50347654 CHEMBL1802587

SMILES: CCCCN(C)c1cnc2ccc3ccc(NS(C)(=O)=O)cc3c(=O)c2c1

InChI Key: InChIKey=DRDZYRKUFMNEGS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50347654 (CHEMBL1802587) Show SMILES CCCCN(C)c1cnc2ccc3ccc(NS(C)(=O)=O)cc3c(=O)c2c1 Show InChI InChI=1S/C20H23N3O3S/c1-4-5-10-23(2)16-12-18-19(21-13-16)9-7-14-6-8-15(22-27(3,25)26)11-17(14)20(18)24/h6-9,11-13,22H,4-5,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...				J Med Chem 54: 4092-108 (2011) Article DOI: 10.1021/jm200112k BindingDB Entry DOI: 10.7270/Q2X34ZFZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50347654 (CHEMBL1802587) Show SMILES CCCCN(C)c1cnc2ccc3ccc(NS(C)(=O)=O)cc3c(=O)c2c1 Show InChI InChI=1S/C20H23N3O3S/c1-4-5-10-23(2)16-12-18-19(21-13-16)9-7-14-6-8-15(22-27(3,25)26)11-17(14)20(18)24/h6-9,11-13,22H,4-5,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of c-MET overexpressed in human GTL-16 cells assessed as phosphorylation at C-terminal Y1349 after 2 hrs by Western blot analysis				J Med Chem 54: 4092-108 (2011) Article DOI: 10.1021/jm200112k BindingDB Entry DOI: 10.7270/Q2X34ZFZ
					More data for this Ligand-Target Pair