BDBM50347733 CHEMBL1802534
SMILES: OC(=O)C1CCN(CC1)c1nc2ccc(cc2nc1N1CCC(CC1)C(O)=O)[N+]([O-])=O
InChI Key: InChIKey=KKBSIBMOIYFEIL-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transforming protein RhoA (Homo sapiens (Human)) | BDBM50347733 (CHEMBL1802534) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of rhoA expressed in Escherichia coli BL21 after 1 hr by G-LISA activation based chemiluminiscence assay | J Med Chem 54: 4508-22 (2011) Article DOI: 10.1021/jm200161c BindingDB Entry DOI: 10.7270/Q2C53M61 | |||||||||||
More data for this Ligand-Target Pair |