BDBM50347864 CHEMBL1802382

SMILES: ClCC(=O)c1ccc2NC(=O)C(=Cc3cnc[nH]3)c2c1

InChI Key: InChIKey=QNMQWPKCKDFOCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Nek2 (Homo sapiens (Human))	BDBM50347864 (CHEMBL1802382) Show SMILES ClCC(=O)c1ccc2NC(=O)C(=Cc3cnc[nH]3)c2c1 |w:12.12| Show InChI InChI=1S/C14H10ClN3O2/c15-5-13(19)8-1-2-12-10(3-8)11(14(20)18-12)4-9-6-16-7-17-9/h1-4,6-7H,5H2,(H,16,17)(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human Nek2 in using [gamma-32P] ATP				J Med Chem 54: 4133-46 (2011) Article DOI: 10.1021/jm200222m BindingDB Entry DOI: 10.7270/Q2QC03TX
					More data for this Ligand-Target Pair