BDBM50348002 CHEMBL1800361

SMILES: CSCC[C@@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C)C(=O)OCc1ccccc1

InChI Key: InChIKey=UIOVGRXEBWMUQT-GDLZYMKVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human))	BDBM50348002 (CHEMBL1800361) Show SMILES CSCC[C@@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H34N4O3S/c1-22-8-6-7-11-26(22)28-16-24(17-32-18-25-19-33-21-34-25)12-13-27(28)30(36)35-29(14-15-39-2)31(37)38-20-23-9-4-3-5-10-23/h3-13,16,19,21,29,32H,14-15,17-18,20H2,1-2H3,(H,33,34)(H,35,36)/t29-/m1/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Myrexis, Inc. Curated by ChEMBL					Assay Description Inhibition of ICMT assessed as accumulation of ras in cytosolic fraction by cell based assay				J Med Chem 54: 5031-47 (2011) Article DOI: 10.1021/jm200249a BindingDB Entry DOI: 10.7270/Q2XW4K49
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