BDBM50348067 CHEMBL1800515

SMILES: CC1(C)CC(CCNc2ccccc2)(CCO1)c1cccs1

InChI Key: InChIKey=WPSPLJVSEOCOIW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human))	BDBM50348067 (CHEMBL1800515) Show SMILES CC1(C)CC(CCNc2ccccc2)(CCO1)c1cccs1 Show InChI InChI=1S/C19H25NOS/c1-18(2)15-19(11-13-21-18,17-9-6-14-22-17)10-12-20-16-7-4-3-5-8-16/h3-9,14,20H,10-13,15H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Myrexis, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminal His6-tagged ICMT assessed as methylation of N-acetyl-S-geranylgeranylcysteine using SAM as methyl donor su...				J Med Chem 54: 5031-47 (2011) Article DOI: 10.1021/jm200249a BindingDB Entry DOI: 10.7270/Q2XW4K49
					More data for this Ligand-Target Pair