BDBM50348068 CHEMBL1800516
SMILES: CC1(C)CC(CCNc2cccc(Cl)c2)(CCO1)c1cccs1
InChI Key: InChIKey=NCUUPWBPTJPQBM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human)) | BDBM50348068 (CHEMBL1800516) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Myrexis, Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal His6-tagged ICMT assessed as methylation of N-acetyl-S-geranylgeranylcysteine using SAM as methyl donor su... | J Med Chem 54: 5031-47 (2011) Article DOI: 10.1021/jm200249a BindingDB Entry DOI: 10.7270/Q2XW4K49 | |||||||||||
More data for this Ligand-Target Pair |