BDBM50348098 CHEMBL1800430

SMILES: NCc1sc2cc(ccc2c1Cl)C#Cc1ccc2CCNCc2c1

InChI Key: InChIKey=YUCPZSNUILZADE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50348098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amiloride-sensitive cation channel 3 (Homo sapiens (Human))	BDBM50348098 (CHEMBL1800430) Show SMILES NCc1sc2cc(ccc2c1Cl)C#Cc1ccc2CCNCc2c1 Show InChI InChI=1S/C20H17ClN2S/c21-20-17-6-4-14(10-18(17)24-19(20)11-22)2-1-13-3-5-15-7-8-23-12-16(15)9-13/h3-6,9-10,23H,7-8,11-12,22H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology method				Bioorg Med Chem Lett 21: 4255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.05.064 BindingDB Entry DOI: 10.7270/Q2DZ08P8
					More data for this Ligand-Target Pair
Amiloride-sensitive cation channel 2, neuronal (Homo sapiens (Human))	BDBM50348098 (CHEMBL1800430) Show SMILES NCc1sc2cc(ccc2c1Cl)C#Cc1ccc2CCNCc2c1 Show InChI InChI=1S/C20H17ClN2S/c21-20-17-6-4-14(10-18(17)24-19(20)11-22)2-1-13-3-5-15-7-8-23-12-16(15)9-13/h3-6,9-10,23H,7-8,11-12,22H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of ASIC1a				Bioorg Med Chem Lett 21: 4255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.05.064 BindingDB Entry DOI: 10.7270/Q2DZ08P8
					More data for this Ligand-Target Pair