BDBM50348282 CHEMBL1800761

SMILES: Clc1cccc(Cl)c1OCc1cccn2c(nnc12)C1CCCCCC1

InChI Key: InChIKey=QALPQXNSSMECGN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50348282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50348282 (CHEMBL1800761) Show SMILES Clc1cccc(Cl)c1OCc1cccn2c(nnc12)C1CCCCCC1 Show InChI InChI=1S/C20H21Cl2N3O/c21-16-10-5-11-17(22)18(16)26-13-15-9-6-12-25-19(23-24-20(15)25)14-7-3-1-2-4-8-14/h5-6,9-12,14H,1-4,7-8,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD-1 expressed in HEK293 cells assessed as [3H]cortisol level by scintillation proximity assay				Bioorg Med Chem Lett 21: 4146-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.101 BindingDB Entry DOI: 10.7270/Q24F1R2Q
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50348282 (CHEMBL1800761) Show SMILES Clc1cccc(Cl)c1OCc1cccn2c(nnc12)C1CCCCCC1 Show InChI InChI=1S/C20H21Cl2N3O/c21-16-10-5-11-17(22)18(16)26-13-15-9-6-12-25-19(23-24-20(15)25)14-7-3-1-2-4-8-14/h5-6,9-12,14H,1-4,7-8,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD-1 expressed in HEK293 EBNA cells using [3H]-cortisone and NADPH by scintillation proximity assay				ACS Med Chem Lett 5: 803-8 (2014) Article DOI: 10.1021/ml500144h BindingDB Entry DOI: 10.7270/Q2N0186W
					More data for this Ligand-Target Pair