BDBM50348324 CHEMBL1800910::US8772288, 3

SMILES: Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC2)c1)C(=O)NC1CC1

InChI Key: InChIKey=UJTKLYGVFXHBJI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50348324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50348324 (CHEMBL1800910 | US8772288, 3) Show SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC2)c1)C(=O)NC1CC1 Show InChI InChI=1S/C22H22N2O2/c1-13-3-4-15(20(25)23-16-6-7-16)11-17(13)14-5-8-18-19(12-14)24-21(26)22(18)9-2-10-22/h3-5,8,11-12,16H,2,6-7,9-10H2,1H3,(H,23,25)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human p38alpha by FRET assay				Bioorg Med Chem Lett 21: 4130-3 (2011) Article DOI: 10.1016/j.bmcl.2011.05.114 BindingDB Entry DOI: 10.7270/Q2NP25DM
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50348324 (CHEMBL1800910 | US8772288, 3) Show SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC2)c1)C(=O)NC1CC1 Show InChI InChI=1S/C22H22N2O2/c1-13-3-4-15(20(25)23-16-6-7-16)11-17(13)14-5-8-18-19(12-14)24-21(26)22(18)9-2-10-22/h3-5,8,11-12,16H,2,6-7,9-10H2,1H3,(H,23,25)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	25
Almirall, S.A. US Patent					Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...				US Patent US8772288 (2014) BindingDB Entry DOI: 10.7270/Q2T152BM
					More data for this Ligand-Target Pair