BDBM50348343 CHEMBL1800314

SMILES: COc1cc(\C=N\NC(=O)CSc2ccncn2)cc(OC)c1OC

InChI Key: InChIKey=CSPIXKAHLZIHDK-UFWORHAWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50348343 (CHEMBL1800314) Show SMILES COc1cc(\C=N\NC(=O)CSc2ccncn2)cc(OC)c1OC Show InChI InChI=1S/C16H18N4O4S/c1-22-12-6-11(7-13(23-2)16(12)24-3)8-19-20-14(21)9-25-15-4-5-17-10-18-15/h4-8,10H,9H2,1-3H3,(H,20,21)/b19-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A assessed as inhibition of hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 21: 4155-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.100 BindingDB Entry DOI: 10.7270/Q2CJ8FRT
					More data for this Ligand-Target Pair