BDBM50348366 CHEMBL1800823

SMILES: COc1cc(\C=N\NC(=O)CSc2cc(C)nc3ccccc23)ccc1Br

InChI Key: InChIKey=UNONQWJYKQRFCG-SSDVNMTOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50348366 (CHEMBL1800823) Show SMILES COc1cc(\C=N\NC(=O)CSc2cc(C)nc3ccccc23)ccc1Br Show InChI InChI=1S/C20H18BrN3O2S/c1-13-9-19(15-5-3-4-6-17(15)23-13)27-12-20(25)24-22-11-14-7-8-16(21)18(10-14)26-2/h3-11H,12H2,1-2H3,(H,24,25)/b22-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A assessed as inhibition of hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 21: 4155-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.100 BindingDB Entry DOI: 10.7270/Q2CJ8FRT
					More data for this Ligand-Target Pair