null

SMILES: CC(C)(C1c2ccccc2Oc2ccccc12)C(=O)Nc1nncs1

InChI Key: InChIKey=UKGFTAPPAPBJRG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50348417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50348417 (CHEMBL1800987) Show SMILES CC(C)(C1c2ccccc2Oc2ccccc12)C(=O)Nc1nncs1 Show InChI InChI=1S/C19H17N3O2S/c1-19(2,17(23)21-18-22-20-11-25-18)16-12-7-3-5-9-14(12)24-15-10-6-4-8-13(15)16/h3-11,16H,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of GS-red from GRapha by fluorescence polarization assay				J Med Chem 53: 8241-51 (2010) Article DOI: 10.1021/jm100957a BindingDB Entry DOI: 10.7270/Q2HX1DPW
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50348417 (CHEMBL1800987) Show SMILES CC(C)(C1c2ccccc2Oc2ccccc12)C(=O)Nc1nncs1 Show InChI InChI=1S/C19H17N3O2S/c1-19(2,17(23)21-18-22-20-11-25-18)16-12-7-3-5-9-14(12)24-15-10-6-4-8-13(15)16/h3-11,16H,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression activity of glucocorticoid receptor in human A549 cells expressing AP-1 assessed as inhibition of PMA-induced AP-1 activity by lucife...				J Med Chem 53: 8241-51 (2010) Article DOI: 10.1021/jm100957a BindingDB Entry DOI: 10.7270/Q2HX1DPW
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50348417 (CHEMBL1800987) Show SMILES CC(C)(C1c2ccccc2Oc2ccccc12)C(=O)Nc1nncs1 Show InChI InChI=1S/C19H17N3O2S/c1-19(2,17(23)21-18-22-20-11-25-18)16-12-7-3-5-9-14(12)24-15-10-6-4-8-13(15)16/h3-11,16H,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression activity of glucocorticoid receptor in human A549 cells assessed as inhibition of IL1beta-stimulated NFkappaB-dependent E-selectin tr...				J Med Chem 53: 8241-51 (2010) Article DOI: 10.1021/jm100957a BindingDB Entry DOI: 10.7270/Q2HX1DPW
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50348417 (CHEMBL1800987) Show SMILES CC(C)(C1c2ccccc2Oc2ccccc12)C(=O)Nc1nncs1 Show InChI InChI=1S/C19H17N3O2S/c1-19(2,17(23)21-18-22-20-11-25-18)16-12-7-3-5-9-14(12)24-15-10-6-4-8-13(15)16/h3-11,16H,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transactivation activity of glucocorticoid receptor ligand binding domain expressed in human NP-1 Hela cells co-expressing GAL4 DNA binding domain by...				J Med Chem 53: 8241-51 (2010) Article DOI: 10.1021/jm100957a BindingDB Entry DOI: 10.7270/Q2HX1DPW
					More data for this Ligand-Target Pair