null

SMILES: CC(=O)C=Cc1c(Oc2cccc(c2)C#N)nc[nH]c1=O

InChI Key: InChIKey=CKMUONQWFJZWIR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50348950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50348950 (CHEMBL1807771) Show SMILES CC(=O)C=Cc1c(Oc2cccc(c2)C#N)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H11N3O3/c1-10(19)5-6-13-14(20)17-9-18-15(13)21-12-4-2-3-11(7-12)8-16/h2-7,9H,1H3,(H,17,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50348950 (CHEMBL1807771) Show SMILES CC(=O)C=Cc1c(Oc2cccc(c2)C#N)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H11N3O3/c1-10(19)5-6-13-14(20)17-9-18-15(13)21-12-4-2-3-11(7-12)8-16/h2-7,9H,1H3,(H,17,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50348950 (CHEMBL1807771) Show SMILES CC(=O)C=Cc1c(Oc2cccc(c2)C#N)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H11N3O3/c1-10(19)5-6-13-14(20)17-9-18-15(13)21-12-4-2-3-11(7-12)8-16/h2-7,9H,1H3,(H,17,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair