BDBM50348968 CHEMBL1808106

SMILES: CCOC(=O)c1ccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)cc1

InChI Key: InChIKey=MKRCJRKXDMLVKG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50348968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM50348968 (CHEMBL1808106) Show SMILES CCOC(=O)c1ccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)cc1 |w:17.17| Show InChI InChI=1S/C17H16N2O5/c1-3-23-17(22)12-5-7-13(8-6-12)24-16-14(9-4-11(2)20)15(21)18-10-19-16/h4-10H,3H2,1-2H3,(H,18,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50348968 (CHEMBL1808106) Show SMILES CCOC(=O)c1ccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)cc1 |w:17.17| Show InChI InChI=1S/C17H16N2O5/c1-3-23-17(22)12-5-7-13(8-6-12)24-16-14(9-4-11(2)20)15(21)18-10-19-16/h4-10H,3H2,1-2H3,(H,18,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50348968 (CHEMBL1808106) Show SMILES CCOC(=O)c1ccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)cc1 |w:17.17| Show InChI InChI=1S/C17H16N2O5/c1-3-23-17(22)12-5-7-13(8-6-12)24-16-14(9-4-11(2)20)15(21)18-10-19-16/h4-10H,3H2,1-2H3,(H,18,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair