null

SMILES: CC(=O)C=Cc1c(Oc2cc(ccc2Cl)C(F)(F)F)nc[nH]c1=O

InChI Key: InChIKey=KNFQKRQPKVNTLJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50348969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM50348969 (CHEMBL1808107) Show SMILES CC(=O)C=Cc1c(Oc2cc(ccc2Cl)C(F)(F)F)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H10ClF3N2O3/c1-8(22)2-4-10-13(23)20-7-21-14(10)24-12-6-9(15(17,18)19)3-5-11(12)16/h2-7H,1H3,(H,20,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50348969 (CHEMBL1808107) Show SMILES CC(=O)C=Cc1c(Oc2cc(ccc2Cl)C(F)(F)F)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H10ClF3N2O3/c1-8(22)2-4-10-13(23)20-7-21-14(10)24-12-6-9(15(17,18)19)3-5-11(12)16/h2-7H,1H3,(H,20,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50348969 (CHEMBL1808107) Show SMILES CC(=O)C=Cc1c(Oc2cc(ccc2Cl)C(F)(F)F)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H10ClF3N2O3/c1-8(22)2-4-10-13(23)20-7-21-14(10)24-12-6-9(15(17,18)19)3-5-11(12)16/h2-7H,1H3,(H,20,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair