BDBM50348972 CHEMBL1808221

SMILES: COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)N=N2)c1

InChI Key: InChIKey=ZRZKGISANQGGBH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50348972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM50348972 (CHEMBL1808221) Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)N=N2)c1 |c:22| Show InChI InChI=1S/C16H16N4O4/c1-9-6-12(20-19-9)13-14(21)17-8-18-15(13)24-11-5-3-4-10(7-11)16(22)23-2/h3-5,7-9,12H,6H2,1-2H3,(H,17,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50348972 (CHEMBL1808221) Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)N=N2)c1 |c:22| Show InChI InChI=1S/C16H16N4O4/c1-9-6-12(20-19-9)13-14(21)17-8-18-15(13)24-11-5-3-4-10(7-11)16(22)23-2/h3-5,7-9,12H,6H2,1-2H3,(H,17,18,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50348972 (CHEMBL1808221) Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)N=N2)c1 |c:22| Show InChI InChI=1S/C16H16N4O4/c1-9-6-12(20-19-9)13-14(21)17-8-18-15(13)24-11-5-3-4-10(7-11)16(22)23-2/h3-5,7-9,12H,6H2,1-2H3,(H,17,18,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins				Bioorg Med Chem Lett 21: 4592-6 (2011) Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V
					More data for this Ligand-Target Pair