BDBM50349081 CHEMBL1807945

SMILES: COc1ccc(cc1)C(=O)c1coc2C=C(Cl)C(=O)C(=O)c12

InChI Key: InChIKey=GTQAMSGDXJLAGF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349081   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptide deformylase (Escherichia coli)	BDBM50349081 (CHEMBL1807945) Show SMILES COc1ccc(cc1)C(=O)c1coc2C=C(Cl)C(=O)C(=O)c12 |t:15| Show InChI InChI=1S/C16H9ClO5/c1-21-9-4-2-8(3-5-9)14(18)10-7-22-12-6-11(17)15(19)16(20)13(10)12/h2-7H,1H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Inhibition of Escherichia coli peptide deformylase after 1 hr by fluorescence polarization based competition assay				Bioorg Med Chem Lett 21: 4528-32 (2011) Article DOI: 10.1016/j.bmcl.2011.05.129 BindingDB Entry DOI: 10.7270/Q2VT1SGT
					More data for this Ligand-Target Pair
Peptide deformylase, mitochondrial (Homo sapiens (Human))	BDBM50349081 (CHEMBL1807945) Show SMILES COc1ccc(cc1)C(=O)c1coc2C=C(Cl)C(=O)C(=O)c12 |t:15| Show InChI InChI=1S/C16H9ClO5/c1-21-9-4-2-8(3-5-9)14(18)10-7-22-12-6-11(17)15(19)16(20)13(10)12/h2-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL					Assay Description Inhibition of human peptide deformylase after 1 hr by fluorescence polarization based competition assay				Bioorg Med Chem Lett 21: 4528-32 (2011) Article DOI: 10.1016/j.bmcl.2011.05.129 BindingDB Entry DOI: 10.7270/Q2VT1SGT
					More data for this Ligand-Target Pair