BDBM50349355 CHEMBL1809213

SMILES: [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6@@H](-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7]

InChI Key: InChIKey=BLGLANVTAVMSKF-PKTZIBPZSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50349355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50349355 (CHEMBL1809213) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6@@H](-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r| Show InChI InChI=1S/C27H38N8O4S/c28-24(29)21-13-11-19(12-14-21)17-33-25(36)23-10-6-16-35(23)26(37)22(9-4-5-15-32-27(30)31)34-40(38,39)18-20-7-2-1-3-8-20/h1-3,7-8,11-14,22-23,34H,4-6,9-10,15-18H2,(H3,28,29)(H,33,36)(H4,30,31,32)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 21: 4860-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50349355 (CHEMBL1809213) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6@@H](-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r| Show InChI InChI=1S/C27H38N8O4S/c28-24(29)21-13-11-19(12-14-21)17-33-25(36)23-10-6-16-35(23)26(37)22(9-4-5-15-32-27(30)31)34-40(38,39)18-20-7-2-1-3-8-20/h1-3,7-8,11-14,22-23,34H,4-6,9-10,15-18H2,(H3,28,29)(H,33,36)(H4,30,31,32)/t22-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of factor 10a				Bioorg Med Chem Lett 21: 4860-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M
					More data for this Ligand-Target Pair
Transmembrane protease serine 11D (Homo sapiens (Human))	BDBM50349355 (CHEMBL1809213) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6@@H](-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r| Show InChI InChI=1S/C27H38N8O4S/c28-24(29)21-13-11-19(12-14-21)17-33-25(36)23-10-6-16-35(23)26(37)22(9-4-5-15-32-27(30)31)34-40(38,39)18-20-7-2-1-3-8-20/h1-3,7-8,11-14,22-23,34H,4-6,9-10,15-18H2,(H3,28,29)(H,33,36)(H4,30,31,32)/t22-,23+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...				Bioorg Med Chem Lett 21: 4860-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50349355 (CHEMBL1809213) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6@@H](-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r| Show InChI InChI=1S/C27H38N8O4S/c28-24(29)21-13-11-19(12-14-21)17-33-25(36)23-10-6-16-35(23)26(37)22(9-4-5-15-32-27(30)31)34-40(38,39)18-20-7-2-1-3-8-20/h1-3,7-8,11-14,22-23,34H,4-6,9-10,15-18H2,(H3,28,29)(H,33,36)(H4,30,31,32)/t22-,23+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of plasmin				Bioorg Med Chem Lett 21: 4860-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M
					More data for this Ligand-Target Pair