Found 4 hits for monomerid = 50349357 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prothrombin
(Homo sapiens (Human)) | BDBM50349357
(CHEMBL1809214)Show SMILES CC(C)(C)OC(=O)CC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C29H39N5O6S/c1-29(2,3)40-25(35)16-15-23(33-41(38,39)19-21-8-5-4-6-9-21)28(37)34-17-7-10-24(34)27(36)32-18-20-11-13-22(14-12-20)26(30)31/h4-6,8-9,11-14,23-24,33H,7,10,15-19H2,1-3H3,(H3,30,31)(H,32,36)/t23-,24+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50349357
(CHEMBL1809214)Show SMILES CC(C)(C)OC(=O)CC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C29H39N5O6S/c1-29(2,3)40-25(35)16-15-23(33-41(38,39)19-21-8-5-4-6-9-21)28(37)34-17-7-10-24(34)27(36)32-18-20-11-13-22(14-12-20)26(30)31/h4-6,8-9,11-14,23-24,33H,7,10,15-19H2,1-3H3,(H3,30,31)(H,32,36)/t23-,24+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description Inhibition of factor 10a |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this Ligand-Target Pair | |
Transmembrane protease serine 11D
(Homo sapiens (Human)) | BDBM50349357
(CHEMBL1809214)Show SMILES CC(C)(C)OC(=O)CC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C29H39N5O6S/c1-29(2,3)40-25(35)16-15-23(33-41(38,39)19-21-8-5-4-6-9-21)28(37)34-17-7-10-24(34)27(36)32-18-20-11-13-22(14-12-20)26(30)31/h4-6,8-9,11-14,23-24,33H,7,10,15-19H2,1-3H3,(H3,30,31)(H,32,36)/t23-,24+/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal... |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM50349357
(CHEMBL1809214)Show SMILES CC(C)(C)OC(=O)CC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C29H39N5O6S/c1-29(2,3)40-25(35)16-15-23(33-41(38,39)19-21-8-5-4-6-9-21)28(37)34-17-7-10-24(34)27(36)32-18-20-11-13-22(14-12-20)26(30)31/h4-6,8-9,11-14,23-24,33H,7,10,15-19H2,1-3H3,(H3,30,31)(H,32,36)/t23-,24+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description Inhibition of plasmin |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this Ligand-Target Pair | |