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BDBM50349368 CHEMBL1809235

SMILES: NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)C(N)=N)NS(=O)(=O)Cc2ccccc2)cc1

InChI Key: InChIKey=KSNMRDRVDBSGNM-FTJBHMTQSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349368   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 11D


(Homo sapiens (Human))		BDBM50349368
PNG
(CHEMBL1809235)
Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)C(N)=N)NS(=O)(=O)Cc2ccccc2)cc1 |r|
Show InChI InChI=1S/C30H35N7O4S/c31-27(32)23-12-8-20(9-13-23)17-25(36-42(40,41)19-22-5-2-1-3-6-22)30(39)37-16-4-7-26(37)29(38)35-18-21-10-14-24(15-11-21)28(33)34/h1-3,5-6,8-15,25-26,36H,4,7,16-19H2,(H3,31,32)(H3,33,34)(H,35,38)/t25-,26+/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
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PC sid
UniChem

Similars
Article
PubMed
 168n/an/an/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...

Bioorg Med Chem Lett 21: 4860-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M
More data for this
Ligand-Target Pair