BDBM50349490 CHEMBL1808630
SMILES: ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccccc1
InChI Key: InChIKey=CXWWNSSAYNBFQJ-VQHVLOKHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50349490 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50349490
(CHEMBL1808630)Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H16N2O4S/c20-17(18-21)9-7-13-6-8-14-11-19(12-15(14)10-13)24(22,23)16-4-2-1-3-5-16/h1-10,21H,11-12H2,(H,18,20)/b9-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description Inhibition of human ERG by automated patch clamp assay |
Bioorg Med Chem Lett 21: 4909-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.015 BindingDB Entry DOI: 10.7270/Q2542NZQ |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50349490
(CHEMBL1808630)Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H16N2O4S/c20-17(18-21)9-7-13-6-8-14-11-19(12-15(14)10-13)24(22,23)16-4-2-1-3-5-16/h1-10,21H,11-12H2,(H,18,20)/b9-7+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description Inhibition of purified recombinant HDAC1 |
Bioorg Med Chem Lett 21: 4909-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.015 BindingDB Entry DOI: 10.7270/Q2542NZQ |
More data for this Ligand-Target Pair | |