BDBM50349498 CHEMBL1808638

SMILES: ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=RBVBZUIONHBODA-KRXBUXKQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50349498 (CHEMBL1808638) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H15F3N2O4S/c19-18(20,21)15-4-6-16(7-5-15)28(26,27)23-10-13-3-1-12(9-14(13)11-23)2-8-17(24)22-25/h1-9,25H,10-11H2,(H,22,24)/b8-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human ERG by automated patch clamp assay				Bioorg Med Chem Lett 21: 4909-12 (2011) Article DOI: 10.1016/j.bmcl.2011.06.015 BindingDB Entry DOI: 10.7270/Q2542NZQ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50349498 (CHEMBL1808638) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H15F3N2O4S/c19-18(20,21)15-4-6-16(7-5-15)28(26,27)23-10-13-3-1-12(9-14(13)11-23)2-8-17(24)22-25/h1-9,25H,10-11H2,(H,22,24)/b8-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of purified recombinant HDAC1				Bioorg Med Chem Lett 21: 4909-12 (2011) Article DOI: 10.1016/j.bmcl.2011.06.015 BindingDB Entry DOI: 10.7270/Q2542NZQ
					More data for this Ligand-Target Pair