BDBM50349986 CHEMBL1813044

SMILES: CC(C)c1ccc(COC2CCN(CC2)c2ncnc(Nc3cccc(NC(C)=O)c3C)n2)cc1

InChI Key: InChIKey=USVHBIUVZZJUHI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50349986 (CHEMBL1813044) Show SMILES CC(C)c1ccc(COC2CCN(CC2)c2ncnc(Nc3cccc(NC(C)=O)c3C)n2)cc1 Show InChI InChI=1S/C27H34N6O2/c1-18(2)22-10-8-21(9-11-22)16-35-23-12-14-33(15-13-23)27-29-17-28-26(32-27)31-25-7-5-6-24(19(25)3)30-20(4)34/h5-11,17-18,23H,12-16H2,1-4H3,(H,30,34)(H,28,29,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Erg expressed in human HEK293 cells by patch-clamp electrophysiological assay				J Med Chem 54: 4427-45 (2011) Article DOI: 10.1021/jm200018k BindingDB Entry DOI: 10.7270/Q2N016W1
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50349986 (CHEMBL1813044) Show SMILES CC(C)c1ccc(COC2CCN(CC2)c2ncnc(Nc3cccc(NC(C)=O)c3C)n2)cc1 Show InChI InChI=1S/C27H34N6O2/c1-18(2)22-10-8-21(9-11-22)16-35-23-12-14-33(15-13-23)27-29-17-28-26(32-27)31-25-7-5-6-24(19(25)3)30-20(4)34/h5-11,17-18,23H,12-16H2,1-4H3,(H,30,34)(H,28,29,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assay				J Med Chem 54: 4427-45 (2011) Article DOI: 10.1021/jm200018k BindingDB Entry DOI: 10.7270/Q2N016W1
					More data for this Ligand-Target Pair