BDBM5035 CHEMBL235747::N-(5-tert-Butyl-3,4-dimethyl-1,3-thiazol-2(3H)-ylidene)benzenesulfonamide::N-[(2Z)-5-tert-butyl-3,4-dimethyl-2,3-dihydro-1,3-thiazol-2-ylidene]benzenesulfonamide::thiazolidenebenzenesulfonamide deriv. 10r

SMILES: Cc1c(s\c(=N/S(=O)(=O)c2ccccc2)n1C)C(C)(C)C

InChI Key: InChIKey=XYRMLZVYRVONRR-PEZBUJJGSA-N

Data: 5 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 5035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM5035 (CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...) Show SMILES Cc1c(s\c(=N/S(=O)(=O)c2ccccc2)n1C)C(C)(C)C Show InChI InChI=1S/C15H20N2O2S2/c1-11-13(15(2,3)4)20-14(17(11)5)16-21(18,19)12-9-7-6-8-10-12/h6-10H,1-5H3/b16-14-	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 13: 949-61 (2005) Article DOI: 10.1016/j.bmc.2004.11.045 BindingDB Entry DOI: 10.7270/Q2C53J1Z
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (K103N) (Human immunodeficiency virus type 1)	BDBM5035 (CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...) Show SMILES Cc1c(s\c(=N/S(=O)(=O)c2ccccc2)n1C)C(C)(C)C Show InChI InChI=1S/C15H20N2O2S2/c1-11-13(15(2,3)4)20-14(17(11)5)16-21(18,19)12-9-7-6-8-10-12/h6-10H,1-5H3/b16-14-	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 13: 949-61 (2005) Article DOI: 10.1016/j.bmc.2004.11.045 BindingDB Entry DOI: 10.7270/Q2C53J1Z
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM5035 (CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...) Show SMILES Cc1c(s\c(=N/S(=O)(=O)c2ccccc2)n1C)C(C)(C)C Show InChI InChI=1S/C15H20N2O2S2/c1-11-13(15(2,3)4)20-14(17(11)5)16-21(18,19)12-9-7-6-8-10-12/h6-10H,1-5H3/b16-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H] CP-55,940 from human CB2 receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 5133-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.005 BindingDB Entry DOI: 10.7270/Q27944C0
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM5035 (CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...) Show SMILES Cc1c(s\c(=N/S(=O)(=O)c2ccccc2)n1C)C(C)(C)C Show InChI InChI=1S/C15H20N2O2S2/c1-11-13(15(2,3)4)20-14(17(11)5)16-21(18,19)12-9-7-6-8-10-12/h6-10H,1-5H3/b16-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgamaS binding assay				Bioorg Med Chem Lett 17: 5133-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.005 BindingDB Entry DOI: 10.7270/Q27944C0
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM5035 (CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...) Show SMILES Cc1c(s\c(=N/S(=O)(=O)c2ccccc2)n1C)C(C)(C)C Show InChI InChI=1S/C15H20N2O2S2/c1-11-13(15(2,3)4)20-14(17(11)5)16-21(18,19)12-9-7-6-8-10-12/h6-10H,1-5H3/b16-14-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H] CP-55,940 from human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 5133-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.005 BindingDB Entry DOI: 10.7270/Q27944C0
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (Y181C) (Human immunodeficiency virus type 1)	BDBM5035 (CHEMBL235747 | N-(5-tert-Butyl-3,4-dimethyl-1,3-th...) Show SMILES Cc1c(s\c(=N/S(=O)(=O)c2ccccc2)n1C)C(C)(C)C Show InChI InChI=1S/C15H20N2O2S2/c1-11-13(15(2,3)4)20-14(17(11)5)16-21(18,19)12-9-7-6-8-10-12/h6-10H,1-5H3/b16-14-	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 13: 949-61 (2005) Article DOI: 10.1016/j.bmc.2004.11.045 BindingDB Entry DOI: 10.7270/Q2C53J1Z
					More data for this Ligand-Target Pair