BDBM50350020 CHEMBL1813016

SMILES: CC(=O)Nc1cccc(Nc2ccnc(n2)N2CCc3ccccc3C2)c1

InChI Key: InChIKey=WFKVZTFEMMHUQI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50350020 (CHEMBL1813016) Show SMILES CC(=O)Nc1cccc(Nc2ccnc(n2)N2CCc3ccccc3C2)c1 Show InChI InChI=1S/C21H21N5O/c1-15(27)23-18-7-4-8-19(13-18)24-20-9-11-22-21(25-20)26-12-10-16-5-2-3-6-17(16)14-26/h2-9,11,13H,10,12,14H2,1H3,(H,23,27)(H,22,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assay				J Med Chem 54: 4427-45 (2011) Article DOI: 10.1021/jm200018k BindingDB Entry DOI: 10.7270/Q2N016W1
					More data for this Ligand-Target Pair