BDBM50350047 CHEMBL1813459
SMILES: CCCCN1C(=O)C(NC(=O)C11CCN(Cc2ccc(Oc3ccccc3)cc2)CC1)C(C)C
InChI Key: InChIKey=JTYBYBHLKINBMN-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50350047 (CHEMBL1813459) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co. Ltd Curated by ChEMBL | Assay Description Inhibition of CYP3A4 | Bioorg Med Chem 19: 4028-42 (2011) Article DOI: 10.1016/j.bmc.2011.05.022 BindingDB Entry DOI: 10.7270/Q2H70G5Q | |||||||||||
More data for this Ligand-Target Pair |