BDBM50350077 CHEMBL1813642

SMILES: Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4sc5CCCc5c34)c(F)c2)c1=O

InChI Key: InChIKey=CSFBGAIYUSFRKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50350077 (CHEMBL1813642) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4sc5CCCc5c34)c(F)c2)c1=O Show InChI InChI=1S/C27H18F2N4O3S/c28-15-6-9-17(10-7-15)33-12-2-4-19(27(33)35)24(34)32-16-8-11-21(20(29)13-16)36-25-23-18-3-1-5-22(18)37-26(23)31-14-30-25/h2,4,6-14H,1,3,5H2,(H,32,34)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met after 60 mins by ELISA				Bioorg Med Chem 19: 3906-18 (2011) Article DOI: 10.1016/j.bmc.2011.05.038 BindingDB Entry DOI: 10.7270/Q2CF9QGW
					More data for this Ligand-Target Pair