BDBM50350179 CHEMBL1811949

SMILES: CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N1CCN(CC1)C(=O)C[C@H](N)C(=O)N1Cc2ccccc2C1

InChI Key: InChIKey=SMAMQYPJDPQBMX-NDEPHWFRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50350179 (CHEMBL1811949) Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N1CCN(CC1)C(=O)C[C@H](N)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C31H44N4O4S/c1-20(2)25-15-26(21(3)4)30(27(16-25)22(5)6)40(38,39)35-13-11-33(12-14-35)29(36)17-28(32)31(37)34-18-23-9-7-8-10-24(23)19-34/h7-10,15-16,20-22,28H,11-14,17-19,32H2,1-6H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50350179 (CHEMBL1811949) Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N1CCN(CC1)C(=O)C[C@H](N)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C31H44N4O4S/c1-20(2)25-15-26(21(3)4)30(27(16-25)22(5)6)40(38,39)35-13-11-33(12-14-35)29(36)17-28(32)31(37)34-18-23-9-7-8-10-24(23)19-34/h7-10,15-16,20-22,28H,11-14,17-19,32H2,1-6H3/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50350179 (CHEMBL1811949) Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N1CCN(CC1)C(=O)C[C@H](N)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C31H44N4O4S/c1-20(2)25-15-26(21(3)4)30(27(16-25)22(5)6)40(38,39)35-13-11-33(12-14-35)29(36)17-28(32)31(37)34-18-23-9-7-8-10-24(23)19-34/h7-10,15-16,20-22,28H,11-14,17-19,32H2,1-6H3/t28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair