BDBM50350186 CHEMBL1814760

SMILES: O=C([C@@H]1C[C@@H](CN1)NCc1ccnc2ccccc12)N1Cc2ccccc2C1

InChI Key: InChIKey=OWMROPBXPMQSFY-UGKGYDQZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50350186 (CHEMBL1814760) Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccnc2ccccc12)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H24N4O/c28-23(27-14-17-5-1-2-6-18(17)15-27)22-11-19(13-26-22)25-12-16-9-10-24-21-8-4-3-7-20(16)21/h1-10,19,22,25-26H,11-15H2/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50350186 (CHEMBL1814760) Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccnc2ccccc12)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H24N4O/c28-23(27-14-17-5-1-2-6-18(17)15-27)22-11-19(13-26-22)25-12-16-9-10-24-21-8-4-3-7-20(16)21/h1-10,19,22,25-26H,11-15H2/t19-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50350186 (CHEMBL1814760) Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccnc2ccccc12)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H24N4O/c28-23(27-14-17-5-1-2-6-18(17)15-27)22-11-19(13-26-22)25-12-16-9-10-24-21-8-4-3-7-20(16)21/h1-10,19,22,25-26H,11-15H2/t19-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair