BDBM50350193 CHEMBL1814632

SMILES: N[C@@H](CC(=O)NC12CC3CC(CC(O)(C3)C1)C2)C(=O)N1Cc2ccccc2C1

InChI Key: InChIKey=SWZHFJHLWCLWQA-IDVCZPGSSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50350193 (CHEMBL1814632) Show SMILES N[C@@H](CC(=O)NC12CC3CC(CC(O)(C3)C1)C2)C(=O)N1Cc2ccccc2C1 |r,TLB:5:6:9:14.12.11,THB:7:8:11:16.6.15,7:6:9.8.14:11,5:6:9.8.14:11,15:6:9:14.12.11,15:12:9:16.7.6,13:12:9:16.7.6| Show InChI InChI=1S/C22H29N3O3/c23-18(20(27)25-11-16-3-1-2-4-17(16)12-25)6-19(26)24-21-7-14-5-15(8-21)10-22(28,9-14)13-21/h1-4,14-15,18,28H,5-13,23H2,(H,24,26)/t14?,15?,18-,21?,22?/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50350193 (CHEMBL1814632) Show SMILES N[C@@H](CC(=O)NC12CC3CC(CC(O)(C3)C1)C2)C(=O)N1Cc2ccccc2C1 |r,TLB:5:6:9:14.12.11,THB:7:8:11:16.6.15,7:6:9.8.14:11,5:6:9.8.14:11,15:6:9:14.12.11,15:12:9:16.7.6,13:12:9:16.7.6| Show InChI InChI=1S/C22H29N3O3/c23-18(20(27)25-11-16-3-1-2-4-17(16)12-25)6-19(26)24-21-7-14-5-15(8-21)10-22(28,9-14)13-21/h1-4,14-15,18,28H,5-13,23H2,(H,24,26)/t14?,15?,18-,21?,22?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50350193 (CHEMBL1814632) Show SMILES N[C@@H](CC(=O)NC12CC3CC(CC(O)(C3)C1)C2)C(=O)N1Cc2ccccc2C1 |r,TLB:5:6:9:14.12.11,THB:7:8:11:16.6.15,7:6:9.8.14:11,5:6:9.8.14:11,15:6:9:14.12.11,15:12:9:16.7.6,13:12:9:16.7.6| Show InChI InChI=1S/C22H29N3O3/c23-18(20(27)25-11-16-3-1-2-4-17(16)12-25)6-19(26)24-21-7-14-5-15(8-21)10-22(28,9-14)13-21/h1-4,14-15,18,28H,5-13,23H2,(H,24,26)/t14?,15?,18-,21?,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 54: 5737-46 (2011) Article DOI: 10.1021/jm200383j BindingDB Entry DOI: 10.7270/Q2G73F37
					More data for this Ligand-Target Pair